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Inherited hypercoagulable states

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An inherited tendency to thrombosis is termed thrombophilia.

The genetic causes of many of the thrombophilias have recently been identified.

In many cases, specific prothrombotic mutations in antithrombotic factors are responsible.

There are three systems which are commonly involved in the pathogenesis of thrombophilia:

  • the antithrombin / heparin system
  • the protein C / protein S system
  • the fibrinolytic system

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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