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Tizanidine

Authoring team

Tizanidine is an alpha2-adrenoceptor agonist which is indicated for spasticity associated with multiple sclerosis or spinal cord injury.

Dosage begins at 2 mg once per day. The dose is increased according to reponse by 2 mg per day every 3-4 days until a maximum dose of 24 mg per day in 4 divided doses is reached.

The main side-effects include:

  • drowsiness
  • dry mouth
  • GI upset

The summary of product characteristics must be consulted before prescribing this drug.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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