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Indications

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Authoring team

Biopsy may assist in:

  • establishing a diagnosis
  • the planning of treatment and monitoring of its effect
  • assessing prognosis

Indications include:

  • persistent proteinuria or haematuria that is associated with renal impairment, for example, as assessed by GFR

  • nephrotic syndrome in patients less than 1 year or above 10 years of age - for children of intermediate age, the cause is most likely to be minimal change nephropathy; as this responds to steroid treatment, the risks of biopsy are thought to outweigh the likely benefits of treatment

  • acute renal failure that persists for more than 4 weeks without any active markers of intrinsic renal disease

  • chronic renal failure with normal sized kidneys

  • the investigation of systemic disorders that affect the kidneys, for example, amyloidosis or systemic lupus erythematosus

  • renal allograft dysfunction

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