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Pathological features

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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The pathological features of cryptogenic fibrosing alveolitis include:

  • migration of large mononuclear cells into the alveolar spaces, associated with acute symptoms
  • thickening of the alveolar walls with fibrosis, associated with chronic disease
  • the pathogenesis is unknown but it is thought there is an alteration in cell-mediated immunity, perhaps activated T lymphocytes increase fibroblastic activity.

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