Hertoghe's sign

Hertoghe's sign (or Queen Anne's sign) is a thinning or loss of the outer third of the eyebrows

• it is a possible sign of hypothyroidism

Also associated with atopic dermatitis although there is study evidence that the association is not significant (2)

Reference:

• Furdell E. Eponymous, anonymous: Queen Anne's sign and the misnaming of a symptom. Lane Furdell E.J Med Biogr. 2007 May;15(2):97-101.
• Pryzybilla B et al. Stigmata of atopic constitution in patients with atopic eczema or atopic respiratory disease. Acta Derm Venereol. 1991;71(5):407-10.