Malignant atrophic papulosis
Dego's disease is a rare, lethal condition affecting the skin, gut and nervous system.
Presentation:
- skin lesions are pathognomonic - circular, porcelain- white, with a depressed centre (4 to 8mm diameter), and slightly elevated erythematous margin.
- arterial lesion - endothelial swelling causing luminal stenosis. There may be fibrinoid necrosis of the wall of the lumen.
Death is generally as a result of intestinal perforation.
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