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Rose-Waaler reaction

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The Rose-Waaler reaction measures the ability of rheumatoid factor to agglutinate sheep erythrocytes that have been coated with rabbit IgG directed against sheep erythrocytes. IgM antibodies are much more effective at agglutinating antigen coated erythrocytes than IgG, and hence IgG is poorly measured by this test. IgG rheumatoid factor can be more effectively measured by other techniques such as radio-immune assay.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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