Virginal or juvenile breast breast hypertrophyis a rare and distinct disorder with the rapid onset of macromastia at the onset of puberty. Most patients with macromastia have breasts which develop normally at puberty but simply reach excessive size (1,2). One review revealed that 108 patients were reported in the medical literature between 1910 and 2006, and amongst these, 57 had a clear diagnosis of juvenile gigantomastia (2).
The aetiology remains elusive but it is thought to be the result of an abnormal stimulation of mammary tissue by normal levels of circulating hormones that manifests as rapid and excessive breast enlargement at any stage in the peripubertal period.
Management may include:
Reference:
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