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Aortic cusp abnormality

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Cusp abnormality, which may be caused by:

  • rheumatic valvulitis:
    • vegetations appear on the aortic cusps during acute rheumatic fever
    • following the acute valvulitis there is fibrotic shrinkage, causing aortic regurgitation and stenosis

  • congenital:
    • often the valve is bicuspid as well as deficient
    • sometimes a ventricular septal defect may cause prolapse of the associated cusp

  • infective endocarditis:
    • usually occurs on an abnormal valve
    • occasionally a normal valve is the site of an infection in either older patients with degenerative changes, drug addicts or with infection with virulent organisms e.g. staphylococcus

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