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Causes of negative cultures

Authoring team

Negative cultures occur in 3 to 20% of cases, usually as a result of prior antibiotic treatment. Other possible causes include:

  • fastidious streptococci and anaerobes
  • Coxiella burnetti, Q fever, requires complement fixation tests
  • Chlamydia - requires immunofluorescence or complement fixation
  • Candida - requires antigen test

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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