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Lipodermatosclerosis describes areas of induration that result from fibrosis of the subcutaneous fat.
Lipodermatosclerosis may complicate chronic venous insufficiency, especially following a deep vein thrombosis.
Increased venous pressure causes the extravasation of red cells into the tissues and subsequent haemosiderin deposition. Often, the affected areas are erythematous initially, but eventually, become purple-brown in colour.
Circumferential lipodermatosclerosis around the ankle may produce the characteristic beer bottle leg.
Treated early, the condition may respond to stanazolol, a fibrinolysis-enhancing agent.