This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages without signing in

Aetiology

Authoring team

Behcet’s syndrome is a systemic venulitis.

The aetiology of Behcet’s disease is not fully understood, however, a combination of genetic and environmental factors may play a role (1):

  • there is a strong HLA association with HLA-B51; this genetic marker is found in around 60% of BD patients (1)
  • Herpes simplex virus-1 (HSV-1) and Streptococcus have been postulated as possible environmental triggers of BD (2)

Reference:

  1. Nair JR, Moots RJ. Behcet’s disease. Clin Med (Lond). 2017 Feb;17(1):71-77. Doi: 10.7861/clinmedicine.17-1-71. PMID: 28148585; PMCID: PMC6297594.
  2. Greco A, De Virgilio A, Ralli M, Ciofalo A, Mancini P, Attanasio G, de Vincentiis M, Lambiase A. Behçet's disease: New insights into pathophysiology, clinical features and treatment options. Autoimmun Rev. 2018 Jun;17(6):567-575.

Related pages

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.