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Drug interactions

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Cyclosporin interacts with several drugs, some causing increased levels of cyclosporin, others, reduced levels.

Drugs that increase the levels of cyclosporin in the blood include:

  • ketoconazole and other anti-fungals
  • some calcium channel blockers e.g. diltiazem and verapamil
  • oral contraceptives
  • erythromycin

Drugs than induce liver enzymes, reduce the levels of cyclosporin in the blood include:

  • barbiturates
  • phenytoin
  • carbamazepine
  • rifampicin

Increased blood levels of cyclosporin may result in toxic side-effects while reduced levels increase the risk of rejection or treatment failure.

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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