has been used for the treatment of male androgenetic alopecia
evidence shows that dutasteride seems to provide a better efficacy compared with finasteride in treating an drogenetic alopecia. The two drugs appear to show similar rates of adverse reactions, especially in sexual dysfunction (1)
a prospective study investigating sexual dysfunction associated with dusteride use for androgenic alopecia in men found (2):
incidence of sexual adverse events was approximately twofold higher in the dutasteride group (16%) than the placebo group (8%) during the double-blind period; the overall incidence of sexual adverse events was lower (5%) during the open-label period
all adverse events were mild to moderate in severity and considered treatment-related
adverse events resolved while on study treatment or after the end of treatment and did not lead to treatment discontinuation.
comparing treatments for male androgenic alopecia
analysis of 23 trials indicate 5mg/d oral dutasteride has highest probability of being most efficacious treatment, followed by (in decreasing order of efficacy): 5mg/d oral finasteride (OF), 5mg/d oral minoxidil (OM), 1mg/d OF, 5% topical minoxidil (TM), 2% TM, & 0.25mg/d OM (3)
3. Gupta AK, Venkataraman M, Talukder M, Bamimore MA. Relative Efficacy of Minoxidil and the 5-alpha Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients: A Network Meta-analysis. JAMA Dermatol. Published online February 02, 2022. doi:10.1001/jamadermatol.2021.5743
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