Drug therapy
Drug therapy for Raynaud's disease is required in those patients suffering:
- intense pain
- functional impairment
- tissue ischaemia, resulting in, for example, digital ulcers
Drugs have four principal targets:
- arterial wall
- blood components
- toxic products of ischaemia
- sympathetic nerves
Response to drugs is idiosyncratic, so it is worth trying more than one drug within a particular class.
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