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Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Tylosis is a congenital hyperkeratosis with pitting of the palms - tylosis palmaris - and of the soles - tylosis plantaris. It is inherited as an autosomal dominant trait.

In some cases, it is associated with oesophageal carcinoma.

Treatment measures include the use of a keratolytic. Systemic treatment with retinoids may be used.

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