This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages without signing in

Combined pituitary test

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The combined pituitary test is used to determine an absence of the normal rises in gonadotrophins, TSH and cortisol after GnRH, TRH and insulin injection.

A basal cortisol measurement must be made before undertaking a combined pituitary test in patients suspected of hypopituitarism. If cortisol is already low, insulin could be dangerous and ACTH should be measured to differentiate between primary and secondary hypocortisolaemia.

Insulin stress test is contraindicated in patients with a history of ischaemic heart disease, ischaemic changes in the ECG or a history of seizures; alternatives testing agents include metyrapone, glucagon or depot synacthen.


Related pages

Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.