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Cyclosporin and St John's wort

Authoring team

St John's wort interacts with cyclosporin and leads to reduced cyclosporin levels.

Suggested management of patients already taking SJW preparations:

  • check cyclosporin levels and stop SJW

  • note that there may be an increase in cyclosporin levels on stopping SJW

  • it may be necessary to adjust the cyclosporin dose

Reference:

  • CEM/CMO/2000/4

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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