Drug-induced hyperkalaemia

Hyperkalemia is a common clinical condition that can be defined as a serum potassium concentration exceeding 5.0 mmol/L. Drug-induced hyperkalemia is the most important cause of increased potassium levels in everyday clinical practice.

Drugs which can cause hyperkalaemia include:

• potassium-sparing diuretics:
  • spironolactone
  • amiloride
    
• other drugs eg NSAIDS, ACE inhibitors, beta blockers, aspirin, heparin, trimethoprim

Reference

1. Salem C et al. Drug-induced hyperkalemia. Drug Saf. 2014 Sep;37(9):677-92.