Growth hormone deficiency
Growth hormone deficiency (GHD) is a rare disorder resulting in:
- short stature in untreated children
- metabolic and psychological morbidity in adults
GHD - defined as suboptimal GH secretion - includes a group of different aetiological disorders. It may be isolated (IGHD) or combined with other anterior and/or posterior pituitary hormone deficiencies.
Combined pituitary hormone deficiency (CPHD) is defined as a deficiency in two or more pituitary hormones.
GHD may be congenital or acquired, sporadic or familial.
Reference
- Ranke MB. Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency. Front Endocrinol (Lausanne). 2021 Sep 1;12:720419.
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