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Investigations

Authoring team

Diagnosis is based on:

  • low serum calcium
  • increased plasma phosphate - low in hypocalcaemia due to intestinal malabsorption or vitamin D deficiency
  • normal alkaline phosphatase - raised in hypocalcaemia due to chronic renal failure
  • skull radiology may reveal basal ganglia calcification
  • PTH: low plasma levels
  • urinary cAMP excretion rises following administration of PTH

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