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Medical treatments of Crohn's in children are similar to adult treatment:

• 5 ASA - given orally or topically - ie per rectum
• immunosuppressive treatments, such as
  • prednisolone - 1-2 mg per/kg/d (maximum 40mg a day) till remission occurs followed by gradual dose reduction over a period of 4-8 weeks (1)
  • azathioprine – can be used as a first line agent in severe cases although it becomes fully effective after at least three months (1)
  • cyclosporin
• antibiotics, particularly if there is anal involvement, for example metronidazole
• infliximab
  • a prospective, multicenter, randomized, open-label study showed that infliximab is effective in the treatment of moderately to severely active Crohn's in children (2)

Reference:

Reference:

• (1) British Society of Paediatrics Gastroenterology Hepatology and Nutrition (BSPGHAN) 2008. Guidelines for the Management of Inflammatory Bowel Disease (IBD) in Children in the United Kingdom
• (2) Hyams J et al.Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children. Gastroenterology. 2007 Mar;132(3):863-73