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Medical treatments of Crohn's in children are similar to adult treatment:

  • 5 ASA - given orally or topically - ie per rectum
  • immunosuppressive treatments, such as
    • prednisolone - 1-2 mg per/kg/d (maximum 40mg a day) till remission occurs followed by gradual dose reduction over a period of 4-8 weeks (1)
    • azathioprine – can be used as a first line agent in severe cases although it becomes fully effective after at least three months (1)
    • cyclosporin
  • antibiotics, particularly if there is anal involvement, for example metronidazole
  • infliximab
    • a prospective, multicenter, randomized, open-label study showed that infliximab is effective in the treatment of moderately to severely active Crohn's in children (2)

Reference:

Reference:

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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