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Elevation of ALP in normal individuals

Authoring team

Alkaline phosphatase may be chronically elevated in normal individuals in the following circumstances:

  • following a fatty meal in people with O or B blood groups

  • third trimester of pregnancy

  • possibly as a familial trait

  • fast-growing adolescents

  • elderly - alkalilne phosphatase levels normally increase gradually between the ages of 40 and 65 years, especially in women; the normal alkaline phosphatase level in an otherwise healthy 65-year old woman is more than 50% higher than the level in a healthy 30-year old woman (1)

Benign transient hyperphosphatasia - see linked item.

Reference:

  • 1) Wolf PL (1978). Clinical significance of an increased or decreased serum alkaline phosphatase. Arch Pathol Lab, 102, 497-501.

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