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GEM - thalassaemia answer part 3

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  • a carrier of a recessive condition is someone with one usual and one altered copy of the gene concerned ("gene variant"). The single copy of the usual gene is sufficient for normal function, and so carriers do not have symptoms of the condition.
  • everyone is a carrier for one or two recessive disorders, but it matters only if both partners are carriers for the same condition.
  • although a person who is a carrier of an autosomal recessive condition is healthy, s/he can have an ill child affected by the condition if their partner is also a carrier for the same recessive condition

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