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Investigations

Authoring team

  • serum IgE levels - elevated secondary to loss of suppressor lymphocyte activity

  • skin prick tests - positive to common allergens

  • Radioallergosorbent testing (RAST) - suggest that IgE is synthesised against the specific antigens of the house dust mite, pollens, cat and dog hair, food allergens

  • skin biopsy reveals chronic inflammation involving lymphocytes, mast cells, histiocytes, eosinophil degranulation

  • white dermographism - rubbing skin elicits a simple white linear streak along the site of pressure with no erythema

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