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Griseofulvin and pregnancy

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Griseofulvin induces aneuploidy and therefore is a potential teratogen. Therefore it has been advised that both men and women should use contraception whilst taking griseofulvin.

  • men - should avoid fathering children during treatment and up to six months after griseofulvin has been stopped

  • women - should not become pregnant whilst taking griseofulvin or within one month of stopping treatment

Reference:

  • Committee on Safety of Medicines (1996). Griseofulvin: contraceptive precautions. Current Problems in Pharmacovigilance, 22, 8.

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