This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages without signing in

Lineage based classification

Authoring team

A classification of acute lymphoblastic leukaemias can be made based on the lineage based system:

C-ALL - CD10 positive:

  • 50% of cases
  • cells are early B lineage as demonstrated by antigen expression and Ig gene rearrangement

T cell:

  • 20% of cases
  • often associated with mediastinal disease and a high WBC

Pre B cell:

  • 20% of cases
  • as for C-ALL but cytoplasmic gamma chains now present

B cell:

  • rare
  • same cell type as seen in Burkitt's lymphoma

Null cell:

  • 9% of cases
  • no specific lineage markers expressed

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.