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Vidopen

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Ampicillin is active against certain Gram positive and negative organisms but is inactivated by penicillinases produced by Staph.aureus, a third of E.coli and a tenth of H.influenzae. Ampicillin is poorly absorbed and absorption is decreased by food in the gut.

Cautions:

  • history of allergy
  • renal impairment
  • RASHES COMMON IN GLANDULAR FEVER AND IN CHRONIC LYMPHATIC LEUKAEMIA

Contra-indications:

  • penicillin hypersensitivity

Side-effects:

  • nausea
  • diarrhoea
  • rashes
  • pseudomembranous colitis
  • see also 'penicillins (general side-effects)'

Routes of administration:

  • oral
    • capsules
    • syrups
  • i.m. injection
  • Slow iv injection
  • i.v. infusion

Ampicillin is also available as an injection or suspension with cloxacillin under the trade names 'Ampiclox' and 'Ampiclox Neonatal'.

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