Pityriasis lichenoides
Pityriasis lichenoides has an acute and chronic phase
- acute form is called Pityriasis lichenoides et varioliformis acuta (PLEVA) or Mucha-Habermann disease
- characterised by red patches that quickly evolve into papules 5-15 mm in diameter
- often covered with a fine mica-like adherent scale
- centre of the papules often becomes filled with pus and blood, or eroded with overlying red-brown crust
- most often occurs on the trunk and extremities but sometimes may also be diffuse and widespread, covering any part of the body
- patients with PLEVA experience burning and itchiness
- chronic form is usually designated as pityriasis licehnoides chronica (PLC)
- more low-grade clinical course than PLEVA
- lesions may appear over the course of several days, weeks or months.
- lesions at various stages may be present at any one time
- the initial lesion is a small pink papule occurs that turns a reddish-brown colour
- generally a fine mica-like adherent scale attached to the central spot develops. This can be peeled off to reveal a shiny, pinkish brown surface
- the spot flattens out spontaneously over several weeks and leaves behind a brown mark, which fades over several months
- most commonly occurs over the trunk, buttocks, arms and legs, but may also occur on the hands, feet, face and scalp.
- lesions are not painful, itchy or irritable
- may be exacerbations and relapses of the condition, which can last for months or years
- two diseases from a spectrum of a self-limited dermatosis with the acute form starting as a maculopapular, erythematous eruption which heals to form superficial variable scars
- lesions occur in crops over several weeks and may continue for months to years
- chronic form is more scaly and less hemorrhagic
- is a predilection for males in the second and third decades
- pityriasis lichenoides is not an uncommon disease in childhood, with age peaks in the preschool and early school-age years. It is usually recurrent, and shows a seasonal variation with onset most often in the fall or winter. In childhood PL, erythromycin is an effective initial treatment choice (1)
- most common on the anterior trunk and flexor surfaces of the proximal portions of the extremities
Management:
- seek expert advice
- pityriasis lichenoides may not always be responsive to treatment
- relapses often occur when treatment is discontinued
- if the rash is asymptomatic
- treatment may not be necessary
- first-line therapies include:
- sun exposure may help to resolve lesions
- sunburn should be avoided
- topical steroids to reduce irritation.
- topical immunomodulators such as tacrolimus or pimecrolimus
- oral antibiotics
- most common antibiotics used are erythromycin and tetracyclines such as doxycycline
- sun exposure may help to resolve lesions
- second-line therapies include:
- phototherapy - artificial ultraviolet radiation treatment with UVB or PUVA has been used with varying success both in patients with PLEVA and in those with PLC
- phototherapy - artificial ultraviolet radiation treatment with UVB or PUVA has been used with varying success both in patients with PLEVA and in those with PLC
Images of pityriasis lichenoides
Reference:
- Blyumin M. Pityriasis lichenoides: pathophysiology, classification, and treatment. Am J Clin Dermatol. 2007;8(1):29-36.
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