Antibiotic therapy
Chronic osteomyelitis is rarely cured by antibiotic therapy alone. Their role is twofold:
- to prevent the spread of infection to healthy bone
- to control acute flares of infection
Sensitivity determination of the pathogens is essential. It is also important that the drugs are non-toxic with long term use and that they penetrate bone well. Good examples are clindamycin and cephalosporins.
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