Diagnostic indications
These include the diagnosis of:
- infection - especially, meningitis, although in cases highly clinically suspicious of this, LP should not delay treatment
- subarachnoid haemorrhage - LP is indicated only for those cases of SAH that are negative on CT scan. Ideally, it should be performed 6 hours after the onset of bleeding to ensure that blood will have reached the lumbar region
- inflammatory conditions:
- Guillain Barre syndrome
- systemic lupus erythematosus
- sarcoidosis
- Behcets syndrome
- multiple sclerosis
- malignant disease:
- lymphoma
- leukaemia
- paraneoplastic disorders
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