The most common tumours causing paraneoplastic neuromyopathies originate in the bronchus and the breast.
Paraneoplastic neuromyopathies include:
It is thought that an immune response to the tumour results in cross-reactive antibodies to nerve and muscle epitopes. A possible example of such an antibody is the "anti-YO" antibody which binds Purkinje cell cytoplasm and is associated with paraneoplastic cerebellar disease.
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