Parkinsonism ( Parkinsonian syndrome)
Parkinsonism is a syndrome that is marked by (1,2):
- hypokinesia (poverty of movement)
- bradykinesia (slowness of movement)
- muscular rigidity - increased tone
- rest tremor - frequency of 4-6 Hz
- posture of universal flexion
The underlying pathology is dopamine depletion within the basal ganglia.
Note:
Parkinsonism (Parkinsonian syndrome) and Parkinson's disease (1,2):
- Parkinsonism (Parkinsonian syndrome) (2)
- this is the term used to describe the syndrome
- it is a common movement disorder
- parkinsonism may also be present as part of another disorder
- in these cases there may be features in addition to features of parkinsonism
- Parkinson's disease
- this is the second most prevalent neurodegenerative disease (after Alzheimer's disease)
- it is the most common cause of parkinsonism
Reference
- Lees AJ et al. Parkinson's disease. Lancet. 2009 Jun 13;373(9680):2055-66.
- NICE. Parkinson’s disease in adults. NICE guideline NG71. Published July 2017, last reviewed December 2024
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