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Interleukin-8

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Interleukin 8 is a low molecular weight cytokine consisting of a relatively short peptide chain. It is produced in:

  • mononuclear phagocytes
  • lymphocytes
  • endothelial cells
  • fibroblasts
  • neutrophils

Its effects are mainly pro-inflammatory and include neutrophil activation, chemotaxis and degranulation.

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