Familial cancer syndromes causing sarcomas
Soft tissue sarcomata are rare tumours accounting for less than 1% of adult tumours but up to 6% of childhood tumours.
A genetic risk factor for sarcoma formation may be present in as many as one third of all patients with childhood sarcomata.
Familial syndromes causing sarcomata include:
- neurofibromatosis
- familial retinoblastoma
- Li-Fraumeni syndrome
- Beckwith-Wiedemann syndrome
- basal cell naevus
- Gardner syndrome
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