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Glycogen (glycolysis)

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Glycogen can liberate glucose for entry into glycolysis. Hepatocytes are capable of this pathway but instead tend to liberate glucose to the blood when cellular reserves are low; this pathway and its regulation are considered further in the submenu on glycogenolysis.

In other cells, the following reactions occur:

  • glycogen phosphorylase cleaves glycogen of 1 glucose molecule that is phosphorylated to produce glucose-1-phosphate
  • phosphoglucomutase converts glucose-1-phosphate into glucose-6-phosphate
  • glucose-6-phosphate is able to enter the glycolytic pathway

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