Diamorphine
1mg SC diamorphine = 3mg oral morphine = 1.5mg SC morphine
These conversion ratios apply to PRN. and regular dosing.
Example 1
60mg morphine slow release tablet BD PO
=total daily dose oral morphine 120mg PO
=60mg SC morphine/24 hrs
=40mg SC diamorphine/24 hrs
Example 2
30mg Oramorph PO PRN
=15mg SC morphine PRN
=10mg SC diamorphine PRN
Diamorphine was traditionally used as the first line injectable strong opioid as it is more water soluble than morphine. Morphine sulphate injection is now used in many centres as the first line injectable strong opioid.
Diamorphine preparations: Injection: 5mg, 10mg, 30mg, 100mg, 500mg in packs of 5 ampoules.
Reference:
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