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Phosphodiesterase inhibitors and HIV protease inhibitors

Authoring team

  • protease inhibitors used in the treatment of HIV can inhibit the breakdown of PDE5 inhibitors and prolong their duration of action - therefore PDE5 inhibitors should be initiated at the lowest possible dose when used in this circumstance

Reference:

  1. British Heart Foundation (Factfile 6/05). Drugs for erectile dysfunction.

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