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Clinical features

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Local effects:

  • blistering and soreness of the skin; cracking, and and shedding of fingernails
  • de-epithelialisation of the cornea and conjunctiva
  • epistaxis or sore throat following inhalation

Systemic effects:

  • abdominal pain, vomiting, diarrhoea
  • pulmonary oedema, cardiac and renal failure, hepatic damage

The final outcome depends on the lung lesion which is dose related; this ranges from minimal changes which are reversible, to pronounced pulmonary oedema, leading to pulmonary fibrosis if the patient survives beyond a few days, and long term respiratory impairment.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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