This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages without signing in

Factor V deficiency

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Deficiencies of Factor's II, V and X are inherited as autosomal recessives. They occur rarely with reported incidences between 1 in 500 000 to 1 in 1 000 000, and result from the production of altered inactive forms of the relevant protein.

Laboratory tests show increased prothrombin and partial thromboplastic times - not corrected by administration of vitamin K; other tests are normal.

Diagnosis is by specific factor assay.

Acquired deficiencies of these diseases may result from:

  • antibodies to the appropriate Factor
  • lupus anticoagulants - e.g. systemic lupus erythematosus
  • systemic amyloidosis - amyloid fibrils bind to Factor X

Notes:

  • descriptive name for factor II is prothrombin
  • descriptive name for factor V is labile factor
  • descriptive name for factor X is Stuart-Power factor

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.