Last reviewed 06/2022

This may be the result of pituitary acidophil cell hypersecretion.

When this condition occurs in childhood then there is stimulation of epiphyseal growth. Patients are excessively tall; and often there is associated sexual immaturity and mental retardation.

Slipping of the upper femoral epiphysis may occur.

Gigantism may rarely be seen in other conditions such as sclerosteosis