NSAIDS compared with simple analgesics

Last reviewed 10/2021

There is evidence that NSAIDs are slightly more effective than than paracetamol in the treatment of osteoarthritis

  • in patients with osteoarthritis of the knee or hip, NSAIDs are slightly better than paracetamol for reducing osteoarthritis related general pain or pain at rest (1)


  1. Wegman A et al. Nonsteroidal antiinflammatory drugs or acetaminophen for osteoarthritis of the hip or knee? A systematic review of evidence and guidelines. J Rheumatol 2004;31:344-54.