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Drug therapy

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Drug therapy for Raynaud's disease is required in those patients suffering:

  • intense pain
  • functional impairment
  • tissue ischaemia, resulting in, for example, digital ulcers

Drugs have four principal targets:

  • arterial wall
  • blood components
  • toxic products of ischaemia
  • sympathetic nerves

Response to drugs is idiosyncratic, so it is worth trying more than one drug within a particular class.

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