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HLA B27

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Associations include:

  • there is a strong association between HLA-B27 and ankylosing spondylitis,
  • become evident that HLA-B27 is common to the entire group of seronegative spondyloarthropathies:
    • which include Reiter's disease, subgroups of intestinal and psoriatic arthropathies, subgroups of juvenile rheumatoid arthritis
  • other associations include:
    • anterior uveitis
    • amyloidosis in rheumatoid arthritis
    • there is also an association which aortic valve ring calcification

Reference:

  • (1) Moll JM, Harlock I, MacRae IF, Wright V. Associations between ankylosing spondylitis, psoriatic arthritis, Reiter's disease, the intestinal arthropathies, and Behçet's syndrome. Medicine (Baltimore) 1974; 53: 343-364.

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