Glutamate dehydrogenase is an enzyme that interconverts glutamate into 2-oxoglutarate and vice-versa. The forward reaction converts NAD or NADP to NADH or NADPH. It also uses water and forms an ammonium ion and a proton.
The forward reaction is one example of oxidative deamination to interconvert an amino acid into a carbohydrate intermediate. Because the enzyme is near-equilibrium, the opposite reaction can occur if there is a reversal of the concentration gradient; this is termed transdeamination.
Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.