This type of retinopathy is the most severe complication of diabetic eye disease and usually follows pre-proliferative retinopathy.
It is seen most commonly in young patients who have been treated by insulin for at least 10 years.
The Wisconsin Epidemiologic Study of Diabetic Retinopathy showed proliferative retinopathy varied from 1.2% to 67% in persons with diabetes for less than ten years and 35 or more years, respectively.
Uncontrolled proliferation results in advanced diabetic eye disease with secondary glaucoma and retinal detachment (1).
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