Last reviewed 01/2021

  • most patients have a chronic intermittent disease course, while 13% have an unremitting disease course and 10% have a prolonged remission
  • less than half require corticosteroids at any point
  • during any given year, approximately 10% are treated with corticosteroids and 30% are treated with 5-aminosalicylates
  • up to 57% of patients require at least one surgical resection
  • about one tenth of patients have prolonged remission (1)
  • nearly 75% of patients have a chronic intermittent course, and about one eighth have an unremitting course
  • if the patient has both small and large bowel disease then about 70% will require surgical intervention.

The atypical form of Crohn's is an acute ileitis. This, unlike other forms of Crohn's, does not recur and may represent a completely different disease.

The excess mortality in patients with Crohn's disease is approximately double that of the general population. This is due to the complications of active disease.


  1. Aliment Pharmacol Ther 2002 Jan;16(1):51-60