This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Hartnup disease

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Hartnup disease is a type of renal aminoaciduria characterised by selective failure of tubular reabsorption of a number of monoamino-monocarboxylic acids such as tryptophan. Deficiency of tryptophan produces pellagra-like symptoms which are accentuated by poor diet. Cerebellar ataxia and a mild mental handicap may be present.

In tandem with the renal deficiency, there is a failure to absorb neutral amino acids from the gut.

This condition is inherited as an autosomal recessive disease.

Treatment is with vitamins from the B complex and nicotinamide.


Related pages

Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.