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Type III cryoglobulin

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Type III cryoglobulins are a polyclonal cryoglobulin in association with a polyclonal rheumatoid factor. The immunoglobulin composition include:

  • IgM-IgG
  • IgM-IgG-IgA

The clinical associations with a type III cryoglobulinaemia include:

  • SLE
  • rheumatoid arthritis
  • EBV
  • Sjogren's disease
  • CMV
  • hepatitis B
  • infective endocarditis
  • Kala-azar
  • leprosy
  • primary biliary cirrhosis
  • post-streptococcal nephritis

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