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Pharmacokinetics

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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There are two enantiomers, the R(+) and S(-) forms, both of which are well absorbed.

The S form is metabolized to 7-hydroxywarfarin and has a half-life of 32 hours. It is four times more potent than the R form.

The R form is metabolized to warfarin alcohols. It has a half-life of 54 hours.

Differences between the characteristics of the two forms are important in some drug interactions.

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